Study of the 3'-ApoB minisatellite performed by PCR in the population of Catalonia (northeast Spain)

Hum Hered. 1995 Mar-Apr;45(2):70-4. doi: 10.1159/000154262.

Abstract

Allele and genotype frequencies for the 3'-ApoB locus were determined in a population sample from Catalonia (northeast Spain) using PCR amplification and nonradioactive detection. In a total of 308 unrelated individuals, 16 alleles and 50 genotypes were observed. The 3'-ApoB locus demonstrated a heterozygosity of 80%. The distribution of genotypes is in agreement with expected values according to the Hardy-Weinberg equilibrium.

Publication types

  • Comparative Study

MeSH terms

  • Alleles*
  • Apolipoproteins B / genetics*
  • Base Sequence
  • Female
  • Gene Frequency*
  • Humans
  • Male
  • Minisatellite Repeats*
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Spain

Substances

  • Apolipoproteins B