Iliopsoas abscesses originating from bacterial lumbar spondylodiscitis were successfully treated by CT-guided percutaneous abscess drainage, antibiotics, and immobilization in two patients. Vertebral fusion of the affected segments was observed in both patients in the follow-up period (1 and 6 years, respectively). Percutaneous abscess drainage can replace surgery for iliopsoas abscesses following vertebral osteomyelitis.