Abstract
A new PCR-based technique, low stringency single specific primer-PCR (LSSP-PCR), has been adapted to produce gene signatures capable of distinguishing human papillomaviruses (HPVs) in clinical specimens. This approach potentially offers a sensitive, inexpensive and high-throughput methodology for precise clinical diagnosis of HPV infections.
MeSH terms
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Base Sequence
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Consensus Sequence
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DNA Primers*
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Genes, Viral
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Humans
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Molecular Sequence Data
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Papillomaviridae / genetics
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Papillomaviridae / isolation & purification*
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Papillomavirus Infections / diagnosis*
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Polymerase Chain Reaction / methods*
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Reproducibility of Results
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Sensitivity and Specificity
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Tumor Virus Infections / diagnosis*