Abstract
Oral administration of the orange drink Tampico containing additionally vitamins A (12.7 mg/l), B (1.81 mg/l), C (86.9 mg/l) to FICBAxC57B1/6 mice has been shown to stabilize erythrocytic membranes and reduce chromosomal aberrations in the murine bone marrow cells induced by cyclophosphamide. There are experimental data on the effects of Tampico on the rate of reparative synthesis in peripheral lymphocytes and blood levels of malonic aldehyde in the mice exposed to model psychoemotional stress.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Animals
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Antimutagenic Agents* / pharmacology
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Ascorbic Acid / administration & dosage
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Beverages*
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Bone Marrow / drug effects
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Bone Marrow / metabolism
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Bone Marrow Cells
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Cells, Cultured
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Chromosome Aberrations
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Citrus*
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Cyclophosphamide / toxicity
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Erythrocyte Membrane / drug effects
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Erythrocyte Membrane / metabolism
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Lipid Peroxidation
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Lymphocytes / drug effects
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Lymphocytes / metabolism
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Male
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Malondialdehyde / blood
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Mice
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Mice, Inbred C57BL
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Mice, Inbred CBA
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Mutagenesis / drug effects
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Vitamin A / administration & dosage
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Vitamin B Complex / administration & dosage
Substances
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Antimutagenic Agents
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Vitamin A
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Vitamin B Complex
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Malondialdehyde
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Cyclophosphamide
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Ascorbic Acid