Stereoselective microbial reduction of 2-keto-3-(N-benzoylamino)-3-phenyl propionic acid ethyl ester. Synthesis of taxol side-chain synthon

Ann N Y Acad Sci. 1995 Mar 31:750:166-74. doi: 10.1111/j.1749-6632.1995.tb19946.x.

Authors

R N Patel¹, A Banerjee, J M Howell, C G McNamee, D Brzozowski, V Nanduri, J K Thottathil, L J Szarka

Affiliation

¹ Department of Microbial Technology, Bristol-Myers Squibb Pharmaceutical Research Institute, New Brunswick, New Jersey 08903, USA.

PMID: 7785844
DOI: 10.1111/j.1749-6632.1995.tb19946.x

No abstract available

MeSH terms

Biomedical Engineering
Oxidation-Reduction
Paclitaxel / chemical synthesis*
Phenylpropionates / chemistry*
Pichia / metabolism
Propionates / chemistry
Stereoisomerism

Substances

2-keto-3-(N-benzoylamino)-3-phenylpropionic acid ethyl ester
Phenylpropionates
Propionates
Paclitaxel