Comparative mapping of the immunoglobulin C epsilon 1 gene (IGHE) in five species of nonhuman primates by fluorescence in situ hybridization

H Tanabe; T Ishida; S Ueda; T Sofuni; H Mizusawa

doi:10.1159/000134042

Comparative mapping of the immunoglobulin C epsilon 1 gene (IGHE) in five species of nonhuman primates by fluorescence in situ hybridization

Cytogenet Cell Genet. 1995;70(3-4):239-42. doi: 10.1159/000134042.

Authors

H Tanabe¹, T Ishida, S Ueda, T Sofuni, H Mizusawa

Affiliation

¹ Laboratory of Cell Bank, National Institute of Health Sciences, Tokyo, Japan.

PMID: 7789180
DOI: 10.1159/000134042

Abstract

The orthologous immunoglobulin C epsilon 1 gene (IGHE) of the common chimpanzee, pygmy chimpanzee, orangutan, white-handed gibbon, and Japanese macaque was assigned to the human chromosome 14 homologue in each species and regionally mapped by fluorescence in situ hybridization to PTR15q32 (common chimpanzee), PPA15q32 (pygmy chimpanzee), PPY15q32 (orangutan), HLA17qter (white-handed gibbon), and MFU7q29 (Japanese macaque). The gene localized to the terminal region of the chromosome in each species, and so this probe provides a new telomeric DNA marker for nonhuman primates.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Line
Chromosome Mapping*
Chromosomes, Human, Pair 14
Genes, Immunoglobulin*
Hominidae / genetics
Humans
Hylobates / genetics
Immunoglobulin epsilon-Chains / genetics*
In Situ Hybridization, Fluorescence
Lymphocytes / immunology
Macaca / genetics
Pan troglodytes / genetics
Pongo pygmaeus / genetics
Primates / genetics*
Primates / immunology
Species Specificity

Substances

Immunoglobulin epsilon-Chains