Assignment of the gene (GLCLC) that encodes the heavy subunit of gamma-glutamylcysteine synthetase to human chromosome 6

Cytogenet Cell Genet. 1995;70(3-4):278-9. doi: 10.1159/000134051.

Abstract

Assignment of the human gene (GLCLC) that encodes the heavy or catalytic subunit of gamma-glutamylcysteine synthetase (glutamate-cysteine ligase; EC 6.3.2.2) to human chromosome 6 was accomplished by hybridization to Southern blotted somatic cell hybrid DNA. This assignment was confirmed by PCR from somatic cell hybrid DNAs.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Base Sequence
  • Blotting, Southern
  • Chromosome Mapping
  • Chromosomes, Human, Pair 6*
  • DNA / analysis
  • DNA Primers
  • DNA, Complementary
  • Glutamate-Cysteine Ligase / genetics*
  • Hominidae / genetics*
  • Humans
  • Macromolecular Substances
  • Molecular Sequence Data
  • Polymerase Chain Reaction

Substances

  • DNA Primers
  • DNA, Complementary
  • Macromolecular Substances
  • DNA
  • Glutamate-Cysteine Ligase