Abstract
Twenty-three monoclonal antibodies raised to Cryptosporidium parvum and 12 raised to C. wrairi reacted with equal intensity with the heterologous species. Despite demonstration of a close immunologic relationship between these two species, C. wrairi did not induce persistent infection in severe combined immunodeficient mice as did C. parvum.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Antibodies, Monoclonal
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Antibodies, Protozoan / immunology*
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Cross Reactions
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Cryptosporidiosis / immunology
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Cryptosporidium / immunology*
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Cryptosporidium / pathogenicity*
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Cryptosporidium parvum / immunology
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Cryptosporidium parvum / pathogenicity
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Female
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Mice
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Mice, SCID
Substances
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Antibodies, Monoclonal
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Antibodies, Protozoan