Gonadotrophin-independent precocious puberty and dyschondrosteosis

J Pediatr Endocrinol. 1994 Jul-Sep;7(3):265-7. doi: 10.1515/jpem.1994.7.3.265.

Abstract

We present a case of gonadotrophin-independent precocious puberty, as seen in McCune-Albright syndrome, and Leri-Weill dyschondrosteosis in a six and a half year-old girl. Her father also reports having early puberty and is similarly affected with dyschondrosteosis. This combination of features has not been reported previously, and represents the association of a skeletal dysplasia with an endocrinopathy.

Publication types

  • Case Reports

MeSH terms

  • Bone Diseases, Developmental / complications*
  • Bone Diseases, Developmental / diagnosis
  • Child
  • Cyproterone Acetate / therapeutic use
  • Female
  • Fibrous Dysplasia, Polyostotic
  • Humans
  • Puberty, Precocious / complications*
  • Puberty, Precocious / diagnosis
  • Puberty, Precocious / drug therapy

Substances

  • Cyproterone Acetate