The human OTF1 locus which overlaps the CD3Z gene is located at 1q22-->q23

R A Sturm; H J Eyre; E Baker; G R Sutherland

doi:10.1159/000133919

The human OTF1 locus which overlaps the CD3Z gene is located at 1q22-->q23

Cytogenet Cell Genet. 1995;68(3-4):231-2. doi: 10.1159/000133919.

Authors

R A Sturm¹, H J Eyre, E Baker, G R Sutherland

Affiliation

¹ Centre for Molecular Biology and Biotechnology, University of Queensland, Brisbane, Australia.

PMID: 7842742
DOI: 10.1159/000133919

Abstract

The human OTF1 locus encoding the Oct-1 protein has previously been mapped to chromosome 1 cen-->q32 by analysis of somatic cell hybrids. We report here the regional localization of OTF1 to 1q22-->q23 by fluorescence in situ hybridization. The physical linkage of the CD3Z gene to the OTF1 transcription unit also refines the location of the CD3Z locus to 1q22-->q23.

MeSH terms

Chromosome Mapping
Chromosomes, Human, Pair 1*
DNA Probes
DNA-Binding Proteins / genetics*
Genetic Linkage
Host Cell Factor C1
Humans
In Situ Hybridization, Fluorescence
Octamer Transcription Factor-1
Transcription Factors / genetics*

Substances

DNA Probes
DNA-Binding Proteins
HCFC1 protein, human
Host Cell Factor C1
Octamer Transcription Factor-1
POU2F1 protein, human
Transcription Factors