Diffuse encephalitic toxoplasmosis is an unusual presentation of toxoplasmosis, in which neuroradiological investigations may not show focal abcesses. Until now it was only reported in immunocompromised patients. In immunocompetent patients, cerebral toxoplasmosis is very unusual, and appears as multiple abcesses, like the classic form in immunocompromised patients. We report the case of an immunocompetent patient who presented a diffuse encephalitic toxoplasmosis; CT and MR examinations showed only nonspecific features of brain swelling and cortical infarct due to vasculitis.