Studies on bone dynamic parameters of iliac periosteum and endosteum in domestic pigs with fluorosis caused by coal-burning contamination were conducted. Bone dynamics of 12 pigs with experimental fluorosis and nine controls both labelled with double tetracycline was investigated. Results showed the distance between two labels on iliac periosteum of domestic pigs with fluorosis shortened and, rates of mineralization and bone matrix formation slowed. It suggested fluorosis played significantly inhibitory roles in bone formation on the periosteal membrane of pig iliac.