A new restriction-site polymorphism in exon 18 of the low density lipoprotein receptor (LDLR) gene

Hum Genet. 1995 Mar;95(3):363-4. doi: 10.1007/BF00225211.

Abstract

A new restriction fragment length polymorphism (RFLP) in exon 18 of the low density lipoprotein receptor (LDLR) gene is described. It should be a useful marker in linkage to familial hypercholesterolemia.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Base Sequence
  • DNA Mutational Analysis
  • DNA Primers
  • Deoxyribonucleases, Type II Site-Specific
  • Humans
  • Hyperlipoproteinemia Type II / genetics*
  • Molecular Sequence Data
  • Polymorphism, Restriction Fragment Length
  • Receptors, LDL / genetics*

Substances

  • DNA Primers
  • Receptors, LDL
  • Deoxyribonucleases, Type II Site-Specific
  • endodeoxyribonuclease AflIII