Short report: prevalence of hantavirus infection in rodents associated with two fatal human infections in California

M J Turell; G W Korch; C A Rossi; D Sesline; B A Enge; D V Dondero; M Jay; G V Ludwig; D Li; C S Schmaljohn

doi:10.4269/ajtmh.1995.52.180

Short report: prevalence of hantavirus infection in rodents associated with two fatal human infections in California

Am J Trop Med Hyg. 1995 Feb;52(2):180-2. doi: 10.4269/ajtmh.1995.52.180.

Authors

M J Turell¹, G W Korch, C A Rossi, D Sesline, B A Enge, D V Dondero, M Jay, G V Ludwig, D Li, C S Schmaljohn, et al.

Affiliation

¹ U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, Maryland.

PMID: 7872450
DOI: 10.4269/ajtmh.1995.52.180

Abstract

Rodents living near two fatal human cases of hantavirus pulmonary syndrome in California were surveyed for evidence of hantavirus infection. Seventeen (15%) (14 Peromyscus maniculatus and one each of P. truei, Eutamias minimus, and Microtus californicus) of 114 rodents tested had evidence (enzyme-linked immunosorbent assay or polymerase chain reaction) of hantavirus infection. This suggests that Peromyscus mice, and P. maniculatus in particular, may be the reservoir for the virus causing this newly recognized disease in California, as previously reported for New Mexico and Arizona.

Publication types

Case Reports

MeSH terms

Adult
Animals
Antibodies, Viral / blood
Arvicolinae
Base Sequence
California / epidemiology
Cross-Sectional Studies
DNA Primers / chemistry
Disease Reservoirs*
Enzyme-Linked Immunosorbent Assay
Fatal Outcome
Female
Hantavirus Infections / epidemiology
Hantavirus Infections / veterinary*
Humans
Male
Molecular Sequence Data
Orthohantavirus / genetics
Orthohantavirus / immunology
Peromyscus*
Polymerase Chain Reaction
Prevalence
RNA, Viral / analysis
Respiratory Distress Syndrome / epidemiology
Rodent Diseases / epidemiology*
Sciuridae

Substances

Antibodies, Viral
DNA Primers
RNA, Viral