Abstract
Cryptococcus neoformans grown with L-dopa was melanized and was less susceptible to amphotericin B. The results suggest that in vivo and in vitro susceptibilities to amphotericin B may differ.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amphotericin B / pharmacology*
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Cryptococcus neoformans / drug effects*
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Cryptococcus neoformans / growth & development
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Cryptococcus neoformans / metabolism
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Levodopa / pharmacology*
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Melanins / biosynthesis
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Microbial Sensitivity Tests
Substances
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Melanins
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Levodopa
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Amphotericin B