Azathioprine myelotoxicity related to elevated 6-thioguanine nucleotides in heart transplantation

Transplant Proc. 1995 Feb;27(1):1298-300.
No abstract available

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Azathioprine / therapeutic use
  • Azathioprine / toxicity*
  • Cyclosporine / blood
  • Cyclosporine / therapeutic use
  • Erythrocytes / drug effects*
  • Erythrocytes / metabolism
  • Female
  • Heart Transplantation / immunology
  • Heart Transplantation / physiology*
  • Humans
  • Leukocyte Count / drug effects
  • Leukopenia / blood
  • Leukopenia / chemically induced*
  • Male
  • Methyltransferases / blood*
  • Methyltransferases / deficiency
  • Middle Aged
  • Reference Values
  • Thioguanine / blood*

Substances

  • Cyclosporine
  • Methyltransferases
  • thiopurine methyltransferase
  • Thioguanine
  • Azathioprine