Decamer peptide derived from the alpha 1 helix of the first domain of HLA-B7 01 prolongs allograft survival in rats with an inhibition of graft infiltrating cell cytotoxicity

MeSH terms

• Animals
• Cytotoxicity, Immunologic*
• Gene Expression / immunology
• Graft Survival / drug effects
• Graft Survival / immunology*
• HLA-B7 Antigen / chemistry
• HLA-B7 Antigen / therapeutic use*
• Heart Transplantation / immunology*
• Heart Transplantation / pathology
• Humans
• Interferon-gamma / biosynthesis
• Interleukin-10 / biosynthesis
• Interleukin-2 / biosynthesis
• Lymphocyte Activation
• Male
• Peptide Fragments / chemistry
• Peptide Fragments / therapeutic use*
• Polymerase Chain Reaction
• Protein Structure, Secondary
• RNA, Messenger / analysis
• RNA, Messenger / biosynthesis
• Rats
• Rats, Inbred Lew
• Spleen / immunology
• T-Lymphocytes / immunology*
• Transplantation, Homologous