Abstract
Four of 59 patients with organic hyperinsulinism had multiple insulinomas and two patients a micro- and macroadenomatosis. Excluding patients with adenomatosis 3 of 10 tumors could be detected preoperatively by ultrasound (5 of 10 by CT). 6 of 7 macroadenomas could be visualized by angiography. Intraoperatively 9 of 10 macroadenomas were palpable. The nonpalpable tumor could be localized by intraoperative ultrasound. Pancreatic resection had better results than multiple enucleations. Excisional biopsy is recommended to exclude nesidioblastosis or microadenomatosis.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adenoma, Islet Cell / diagnosis
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Adenoma, Islet Cell / pathology
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Adenoma, Islet Cell / surgery
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Adolescent
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Adult
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Diagnostic Imaging
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Female
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Humans
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Hyperinsulinism / diagnosis
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Hyperinsulinism / pathology
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Hyperinsulinism / surgery
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Insulinoma / diagnosis
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Insulinoma / pathology
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Insulinoma / surgery*
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Male
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Middle Aged
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Neoplasms, Multiple Primary / diagnosis
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Neoplasms, Multiple Primary / pathology
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Neoplasms, Multiple Primary / surgery*
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Pancreas / pathology
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Pancreatectomy
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Pancreatic Neoplasms / diagnosis
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Pancreatic Neoplasms / pathology
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Pancreatic Neoplasms / surgery*