Restriction fragment length polymorphism analysis of Cryptococcus neoformans isolates from environmental (pigeon excreta) and clinical sources in New York City

J Clin Microbiol. 1994 May;32(5):1188-92. doi: 10.1128/jcm.32.5.1188-1192.1994.

Abstract

Restriction fragment length polymorphism analysis of environmental (pigeon excreta) and clinical Cryptococcus neoformans var. neoformans isolates in a limited geographic area distinguished 6 strains among 8 environmental isolates and 12 strains among 17 clinical isolates. Clusters of patients with three strains types accounted for 47% of clinical isolates. Despite this diversity, two strains were shared by environmental and clinical isolates.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • AIDS-Related Opportunistic Infections / epidemiology
  • AIDS-Related Opportunistic Infections / microbiology
  • Animals
  • Columbidae / microbiology*
  • Cryptococcosis / epidemiology
  • Cryptococcosis / microbiology*
  • Cryptococcosis / transmission
  • Cryptococcus neoformans / genetics*
  • Cryptococcus neoformans / isolation & purification*
  • DNA, Fungal / genetics
  • Disease Reservoirs
  • Environmental Microbiology
  • Feces / microbiology
  • Humans
  • New York City / epidemiology
  • Opportunistic Infections / epidemiology
  • Opportunistic Infections / microbiology
  • Polymorphism, Restriction Fragment Length*

Substances

  • DNA, Fungal