Analysis of a PstI polymorphism of the human erythrocyte band 3 gene (EPB3)

P B Jenkins; P G Gallagher; B G Forget

doi:10.1111/j.1365-2141.1993.tb03232.x

Analysis of a PstI polymorphism of the human erythrocyte band 3 gene (EPB3)

Br J Haematol. 1993 Dec;85(4):816-8. doi: 10.1111/j.1365-2141.1993.tb03232.x.

Authors

P B Jenkins¹, P G Gallagher, B G Forget

Affiliation

¹ Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06510.

PMID: 7918052
DOI: 10.1111/j.1365-2141.1993.tb03232.x

Abstract

The genomic structure of a 1.5 kb region near the 5' end of the human erythrocyte band 3 gene (EPB3) was determined and the location of a two-allele PstI polymorphism in this region identified. Using this information, a polymerase chain reaction (PCR)-based assay was designed for rapid, simple identification of the PstI polymorphism.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Anion Exchange Protein 1, Erythrocyte / genetics*
Base Sequence
Blotting, Southern
Deoxyribonucleases, Type II Site-Specific
Erythrocytes / chemistry*
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

Substances

Anion Exchange Protein 1, Erythrocyte
CTGCAG-specific type II deoxyribonucleases
Deoxyribonucleases, Type II Site-Specific