Transcriptional activation. How lambda repressor talks to RNA polymerase

Curr Biol. 1994 May 1;4(5):440-2. doi: 10.1016/s0960-9822(00)00097-x.

Abstract

The bacteriophage lambda repressor protein can activate or repress transcription. Amino-acid substitutions in the sigma subunit of RNA polymerase affect repressor-stimulated transcription, shedding light on the activation process.

Publication types

  • Review

MeSH terms

  • DNA-Binding Proteins*
  • DNA-Directed RNA Polymerases / genetics
  • DNA-Directed RNA Polymerases / metabolism
  • Escherichia coli / genetics
  • Escherichia coli / metabolism
  • Models, Genetic
  • Repressor Proteins / metabolism
  • Sigma Factor / genetics
  • Sigma Factor / metabolism
  • Transcriptional Activation*
  • Viral Proteins
  • Viral Regulatory and Accessory Proteins

Substances

  • DNA-Binding Proteins
  • Repressor Proteins
  • Sigma Factor
  • Viral Proteins
  • Viral Regulatory and Accessory Proteins
  • phage repressor proteins
  • DNA-Directed RNA Polymerases