Hydrolaparoscopy in the rabbit: a fine model for the development of operative fetoscopy

Am J Obstet Gynecol. 1994 Oct;171(4):1139-42. doi: 10.1016/0002-9378(94)90052-3.

Abstract

Objective: Our goal was to become adept at performing laparoscopic procedures within a fluid medium and at using miniature instruments in a small animal model.

Study design: Adult female New Zealand rabbits underwent carbon dioxide laparoscopy while they were under general anesthesia with the use of 2 mm instruments. The abdominal cavity was filled with lactated Ringer's solution. Visualization of the intraabdominal organs and surgical procedures were performed below the fluid level.

Results: Excellent visualization of the abdominal organs below the fluid level was obtained. Several surgical tasks were accomplished, including cutting and coagulation of the uterine horns with monopolar electrocautery, creation of a defect in the mesovarium and mesometrium, extracorporeal knot tying, and intraabdominal cutting of suture material. Relatively high amounts of energy were needed during electrocautery within the liquid medium (> 25 W). Occasional fluid and gas leakage through the skin punctures was prevented with accessory clamps.

Conclusion: Hydrolaparoscopy can be performed in the rabbit with miniature instruments. As it simulates the human intraamniotic environment, it is a useful model for the development of operative fetoscopy.

MeSH terms

  • Abdomen
  • Animals
  • Female
  • Fetoscopy* / methods
  • Instillation, Drug
  • Isotonic Solutions / administration & dosage
  • Laparoscopy* / methods
  • Models, Biological*
  • Rabbits
  • Ringer's Lactate

Substances

  • Isotonic Solutions
  • Ringer's Lactate