Abstract
We describe a complex polymorphic repeat discovered analyzing YAC 225B1, which spans the region between the HLA-A and HLA-E loci. The repeat consists of a variable number of the nucleotide A followed by a variable number of the trinucleotide AAG [(A)n(AAG)n]. Three different alleles were detected with an observed heterozygosity of 0.30.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alleles
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Base Sequence
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Genes, MHC Class I / genetics*
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HLA Antigens / genetics
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HLA-A Antigens / genetics
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HLA-E Antigens
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Histocompatibility Antigens Class I / genetics
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Humans
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Molecular Sequence Data
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Oligodeoxyribonucleotides
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Polymorphism, Genetic*
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Repetitive Sequences, Nucleic Acid*
Substances
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HLA Antigens
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HLA-A Antigens
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Histocompatibility Antigens Class I
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Oligodeoxyribonucleotides