Abstract
A novel polymorphism in the coding sequence of the human RET proto-oncogene is described. The RET proto-oncogene maps to chromosome 10q11.2, and is involved in multiple endocrine neoplasia (MEN 2A, MEN 2B), familial medullary thyroid carcinoma and Hirschsprung's disease.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Base Sequence
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Chromosomes, Human, Pair 10
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Drosophila Proteins*
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Gene Frequency
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Humans
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Molecular Sequence Data
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Polymorphism, Restriction Fragment Length*
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Proto-Oncogene Mas
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Proto-Oncogene Proteins / genetics*
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Proto-Oncogene Proteins c-ret
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Proto-Oncogenes / genetics*
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Receptor Protein-Tyrosine Kinases / genetics*
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White People / genetics
Substances
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Drosophila Proteins
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MAS1 protein, human
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Proto-Oncogene Mas
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Proto-Oncogene Proteins
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Proto-Oncogene Proteins c-ret
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Receptor Protein-Tyrosine Kinases
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Ret protein, Drosophila