Abstract
The nucleotide sequence of the major outer membrane protein gene (omp1) was determined for three geographically distinct lymphogranuloma venereum isolates which were serologically untypeable. The three omp1 sequences were hybrids of serovars L1 and L2, containing a putative DNA recombination site in variable segment 2. Efforts to manipulate the chlamydial genome in vitro by recombination should be intensified.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Bacterial Outer Membrane Proteins / genetics*
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Base Sequence
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Chlamydia Infections / microbiology
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Chlamydia trachomatis / classification
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Chlamydia trachomatis / genetics*
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Eye Infections, Bacterial / microbiology
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Female
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Humans
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Lymphogranuloma Venereum / epidemiology
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Lymphogranuloma Venereum / microbiology*
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Molecular Sequence Data
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Porins*
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Recombination, Genetic*
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Sequence Analysis, DNA
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Sequence Homology, Nucleic Acid
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Serotyping
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South Africa / epidemiology
Substances
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Bacterial Outer Membrane Proteins
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Porins
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omp1 protein, Chlamydia trachomatis
Associated data
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GENBANK/L35605
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GENBANK/L35606