[Is the risk of pneumocystosis predictable in Wegener's disease?]

B Godeau; J L Mainardi; E Hachulla; L Guillevin; F Roudot-Thoraval; P Remy; L T Huong-Boutin; A Schaeffer; J C Piette

doi:10.1016/s0248-8663(05)80142-0

[Is the risk of pneumocystosis predictable in Wegener's disease?]

Rev Med Interne. 1993;14(10):1025. doi: 10.1016/s0248-8663(05)80142-0.

[Article in French]

Authors

B Godeau¹, J L Mainardi, E Hachulla, L Guillevin, F Roudot-Thoraval, P Remy, L T Huong-Boutin, A Schaeffer, J C Piette

Affiliation

¹ Service de médecine interne I, hôpital Henri Mondor, Créteil.

PMID: 8009021
DOI: 10.1016/s0248-8663(05)80142-0

Abstract

Twelve cases of Pneumocystis pneumonia in patients with Wegener's granulomatosis were compared with a control-group of 32 patients. Our study showed that the dose of cyclophosphamide received in the first three months and a profound lymphocytopenia were strongly predictive of a risk of Pneumocystis carinii pneumonia in these patients.

Publication types

English Abstract

MeSH terms

Cyclophosphamide / adverse effects
Granulomatosis with Polyangiitis / complications*
Humans
Lymphopenia / chemically induced
Pneumonia, Pneumocystis / etiology*
Pneumonia, Pneumocystis / prevention & control
Retrospective Studies
Risk Factors

Substances

Cyclophosphamide