Lipomembranous (membranocystic) changes associated with morphea: a clinicopathologic review of three cases

J Am Acad Dermatol. 1994 Aug;31(2 Pt 1):246-50. doi: 10.1016/s0190-9622(94)70156-3.

Abstract

Lipomembranous (membranocystic) changes represent a distinctive form of pathology in adipose tissue. Although first described in the rare neurodegenerative disorder now called Nasu-Hakola disease, this change has also been observed in a variety of relatively common inflammatory and noninflammatory dermatoses. We report three cases of morphea associated with marked lipomembranous (membranocystic) changes in the subcutaneous adipose tissue.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / pathology*
  • Adult
  • Aged
  • Back
  • Biopsy
  • Female
  • Humans
  • Leg
  • Lipodystrophy / pathology*
  • Scleroderma, Localized / pathology*
  • Skin / pathology*