Effect of pre-operative skin preparation on post-operative wound infection

J Postgrad Med. 1993 Jul-Sep;39(3):134-6.

Abstract

A prospective randomised trial was carried out to compare the efficacy of method of scrubbing the operative site for ten minutes with an antiseptic (GpA; n = 68) with a simplified method where the antiseptic was merely painted onto the operation site (GpB; n = 67). The median age, sex distribution and the types of procedures done in each group were similar as was the antibiotic policy. There were a total of 11 patients who got infected, 6 in the group A and 5 in the group B. No significant difference could be demonstrated in the infection rates between the two groups. It is concluded that the old method of prolonged scrubbing the operation site can safely be omitted to a more simplified version.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Anti-Infective Agents, Local / administration & dosage*
  • Cetrimonium
  • Cetrimonium Compounds / administration & dosage
  • Chlorhexidine / administration & dosage
  • Disinfection / methods*
  • Female
  • Humans
  • Iodine / administration & dosage
  • Male
  • Prospective Studies
  • Surgical Wound Infection / prevention & control*

Substances

  • Anti-Infective Agents, Local
  • Cetrimonium Compounds
  • Iodine
  • Chlorhexidine
  • Cetrimonium