Modification of interpersonal psychotherapy with depressed adolescents (IPT-A): phase I and II studies

J Am Acad Child Adolesc Psychiatry. 1994 Jun;33(5):695-705. doi: 10.1097/00004583-199406000-00011.

Abstract

Objective: To test the acceptability and efficacy of interpersonal psychotherapy for depressed adolescents (IPT-A).

Method: In phase I, therapeutic methods were explored and refined in a small sample of depressed adolescents (n = 5). In phase II, 14 depressed adolescents entered a 12-week open clinical trial of IPT-A; after independent evaluation. Subjects were assessed using a semistructured diagnostic interview, self-report, and clinician-administered instruments, at six time points: evaluation week, and weeks 0, 2, 4, 8, and 12.

Results: In phase I, treatment was modified to meet the needs of an adolescent population and was standardized in a treatment manual. The results of phase II indicated a significant decrease in adolescents' depressive symptomatology and symptoms of psychological and physical distress, as well as a significant improvement in functioning over the course of treatment. At termination, none of the subjects met DSM-III-R criteria for any depressive disorder.

Conclusions: IPT-A appears to be a promising therapy for depressed adolescents. However, because of the limitations of the current study, a larger randomized controlled clinical trial is still needed to test its efficacy.

Publication types

  • Clinical Trial
  • Clinical Trial, Phase I
  • Clinical Trial, Phase II
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Combined Modality Therapy
  • Depressive Disorder / psychology
  • Depressive Disorder / therapy*
  • Family Therapy / methods
  • Female
  • Humans
  • Male
  • Patient Care Team
  • Personality Assessment
  • Personality Development
  • Psychotherapy / methods*
  • Social Adjustment
  • Treatment Outcome