Rest tremor and extrapyramidal symptoms after midbrain haemorrhage: clinical and 18F-dopa PET evaluation

J Neurol Neurosurg Psychiatry. 1994 Aug;57(8):987-9. doi: 10.1136/jnnp.57.8.987.

Abstract

A 25 year old man had an acute subarachnoid haemorrhage due to the rupture of a right peduncular subthalamic arteriovenous malformation. Seven months later he developed a left rest tremor associated with mild bilateral extrapyramidal symptoms and responsive to levodopa treatment. Surface EMG recording showed synchronous activity of agonist and antagonist muscles in the left limbs. A PET 18F-dopa study showed a large decrease of the Ki value in the right striatum. One year after the stroke a persistent postural component developed in the tremor.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Basal Ganglia Diseases / drug therapy
  • Basal Ganglia Diseases / etiology*
  • Basal Ganglia Diseases / physiopathology
  • Dihydroxyphenylalanine / analogs & derivatives*
  • Electromyography
  • Fluorine Radioisotopes*
  • Humans
  • Intracranial Arteriovenous Malformations / complications*
  • Levodopa / therapeutic use
  • Male
  • Mesencephalon*
  • Posture / physiology
  • Rest*
  • Rupture, Spontaneous
  • Subarachnoid Hemorrhage / complications*
  • Subarachnoid Hemorrhage / diagnostic imaging*
  • Thalamus*
  • Tomography, Emission-Computed*
  • Tremor / drug therapy
  • Tremor / etiology*
  • Tremor / physiopathology

Substances

  • Fluorine Radioisotopes
  • fluorodopa F 18
  • Levodopa
  • Dihydroxyphenylalanine