Tree-structured proportional hazards regression modeling

Biometrics. 1994 Jun;50(2):471-85.

Abstract

A method for fitting piecewise proportional hazards models to censored survival data is described. Stratification is performed recursively, using a combination of statistical tests and residual analysis. The bootstrap is employed to keep the probability of a Type I error (the error of discovering two or more strata when there is only one) of the method close to a predetermined value. The proposed method can thus also serve as a formal goodness-of-fit test for the proportional hazards model. Real and simulated data are used for illustration.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Age Factors
  • Heart Transplantation / mortality
  • Heart Transplantation / statistics & numerical data*
  • Humans
  • Liver Transplantation / mortality
  • Liver Transplantation / statistics & numerical data*
  • Middle Aged
  • Predictive Value of Tests
  • Proportional Hazards Models*
  • Survival Analysis*
  • Time Factors