Abstract
Expression of staphylocoagulase by agr+ Staphylococcus aureus depends on the growth phase, being maximal during exponential growth and decreasing sharply postexponentially, while an agr-deleted strain continuously expresses an intermediate level of coagulase. Therefore, coagulase expression appears to be both positively and negatively modulated by an agr-dependent mechanism.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Coagulase / biosynthesis*
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Gene Deletion
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Gene Expression
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Gene Expression Regulation, Bacterial
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Gene Expression Regulation, Enzymologic
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Genes, Bacterial
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Genes, Regulator*
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Kinetics
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RNA, Messenger / biosynthesis
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Staphylococcus aureus / enzymology*
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Staphylococcus aureus / genetics
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Staphylococcus aureus / growth & development
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Transcription, Genetic