A secondary localisation of an epithelioid sarcoma appeared on the inguinal scar of a groin flap in a 28 years-old woman, 14 months after resection and coverage of the primary tumor in the palm of the right hand. The evolution was free of recurrence or metastasis, with a two-year follow-up, after surgical resection of the inguinal tumor, radiotherapy and chemotherapy. Secondary localisation of tumors in musculo-cutaneous flaps can be observed after head and neck or chest wall surgery. Contiguity propagation, or venous or lymphatic dissemination are the usual mechanisms. One must realised a biopsy preliminary to the resection of a suspicious tumor of upper or lower limb. When one needs a flap for reconstruction, one must prefer to use a local flap.