Aminoacyl-tRNAs. Diversity before and unity after interaction with EF-Tu:GTP

FEBS Lett. 1994 Aug 29;351(1):137-9. doi: 10.1016/0014-5793(94)00770-5.

Abstract

Evidence is presented for a new role for elongation factor EF-Tu. This involves conformational restraint or conformational selection of any aminoacyl-tRNA for channeling it to the ribosomal decoding site.

MeSH terms

  • Guanosine Triphosphate / metabolism*
  • Nucleic Acid Conformation
  • Peptide Elongation Factor Tu / metabolism*
  • RNA, Transfer, Amino Acyl / chemistry
  • RNA, Transfer, Amino Acyl / metabolism*

Substances

  • RNA, Transfer, Amino Acyl
  • Guanosine Triphosphate
  • Peptide Elongation Factor Tu