Evaluation of five immunoassays for detection of Chlamydia psittaci in cloacal and conjunctival specimens from turkeys

J Clin Microbiol. 1994 Jun;32(6):1470-4. doi: 10.1128/jcm.32.6.1470-1474.1994.

Abstract

Five commercially available immunoassays were evaluated for the detection of Chlamydia psittaci in cloacal and conjunctival swabs from industrially raised turkeys: IMAGEN (DAKO Diagnostics, Ely, Cambridgeshire, United Kingdom), Chlamydia CEL-VET IF (Cellabs, Brookvale, Australia), IDEIA (DAKO Diagnostics), CELISA (Cellabs), and CLEARVIEW (Unipath, Bedford, United Kingdom). Results were compared with isolation in Buffalo Green Monkey cells as a reference method. For the conjunctival samples, the sensitivities of the IMAGEN test, the Chlamydia CEL-VET IF test, the IDEIA, the CELISA, and the CLEARVIEW test were found to be 100, 66, 0, 0, and 0%, respectively, as compared to the reference test. Also for the conjunctival samples, the specificities of the IMAGEN test, the Chlamydia CEL-VET IF test, and the IDEIA were found to be 100, 11, and 92.8%, respectively. For the cloacal specimens, the sensitivities of the IMAGEN test, the Chlamydia CEL-VET IF test, the IDEIA, the CELISA, and the CLEARVIEW test were found to be 100, 93.3, 26.6, 0, and 53.3%, respectively. Also for the cloacal specimens, the specificities of the IMAGEN test, the Chlamydia CEL-VET IF test, the IDEIA, and the CLEARVIEW test were found to be 92, 12, 100, and 88%, respectively. The IMAGEN test was the most sensitive and specific direct chlamydia antigen detection test for cloacal and conjunctival samples from turkeys.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chlamydophila psittaci / immunology
  • Chlamydophila psittaci / isolation & purification*
  • Cloaca / microbiology*
  • Conjunctiva / microbiology*
  • Conjunctivitis, Bacterial / diagnosis
  • Conjunctivitis, Bacterial / microbiology
  • Conjunctivitis, Bacterial / veterinary*
  • Enzyme-Linked Immunosorbent Assay
  • Evaluation Studies as Topic
  • Fluorescent Antibody Technique
  • Immunoassay*
  • Poultry Diseases / microbiology*
  • Psittacosis / diagnosis
  • Psittacosis / microbiology
  • Psittacosis / veterinary*
  • Reagent Kits, Diagnostic*
  • Sensitivity and Specificity
  • Turkeys / microbiology*

Substances

  • Reagent Kits, Diagnostic