Localisation of the gene for multiple endocrine neoplasia type 2A to a 480 kb region in chromosome band 10q11.2

S E Mole; L M Mulligan; C S Healey; B A Ponder; A Tunnacliffe

doi:10.1093/hmg/2.3.247

Localisation of the gene for multiple endocrine neoplasia type 2A to a 480 kb region in chromosome band 10q11.2

Hum Mol Genet. 1993 Mar;2(3):247-52. doi: 10.1093/hmg/2.3.247.

Authors

S E Mole¹, L M Mulligan, C S Healey, B A Ponder, A Tunnacliffe

Affiliation

¹ Department of Pathology, University of Cambridge, UK.

PMID: 8098978
DOI: 10.1093/hmg/2.3.247

Abstract

A YAC contig has been constructed spanning 1.1 Mb of human chromosome band 10q11.2 which encompasses three markers (D10S141, RET, D10S94) closely linked to the gene for MEN 2A. This physical linkage group is ordered cen-D10S141-RET-D10S94-qter, and must include MEN2A, which lies in a 480 kb region between flanking markers D10S141 and D10S94.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
Chromosome Mapping
Chromosomes, Fungal
Chromosomes, Human, Pair 10*
DNA / genetics
Gene Library
Genetic Linkage
Genetic Markers
Genome, Human
Humans
Molecular Sequence Data
Multiple Endocrine Neoplasia / genetics*
Oncogenes*
Restriction Mapping

Substances

Genetic Markers
DNA