Abstract
Hematopoietic stem cells are capable of multi-lineage differentiation to all blood cell types as well as self-renewal and radioprotection. Thy-1.1lo Lin-/lo Sca-1+ cells are a heterogeneous mixture of quiescent and self-renewing hematopoietic stem cells as well as multi-lineage expanding cells.
MeSH terms
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Animals
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Antigens, Differentiation / metabolism
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Antigens, Surface / genetics
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Cell Differentiation
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Gene Rearrangement
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Hematopoiesis
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Hematopoietic Stem Cells / cytology*
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Hematopoietic System / embryology
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Hematopoietic System / growth & development
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Immunophenotyping
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Membrane Glycoproteins / genetics
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Mice
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Mice, Inbred Strains / genetics
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Mice, Inbred Strains / immunology
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Thy-1 Antigens
Substances
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Antigens, Differentiation
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Antigens, Surface
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Membrane Glycoproteins
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Thy-1 Antigens