Abstract
Desensitization to sulphasalazine was successful in 16 of 21 (76%) arthritic patients who previously had skin rash from sulphasalazine (success rate: 8 of 13, or 62%) or sulphonamide (success rate: 8 out of 8 patients). Desensitization to sulphasalazine is a simple outpatient procedure which allows many subjects who develop a skin rash to sulphonamide or sulphasalazine to start or continue sulphasalazine treatment.
MeSH terms
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Adult
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Aged
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Arthritis / drug therapy*
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Arthritis / immunology
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Desensitization, Immunologic*
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Drug Eruptions / etiology
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Drug Eruptions / immunology
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Female
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Humans
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Male
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Middle Aged
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Spondylitis, Ankylosing / drug therapy
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Sulfasalazine / adverse effects
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Sulfasalazine / immunology*
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Sulfasalazine / therapeutic use*
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Sulfonamides / adverse effects
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Sulfonamides / immunology
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Sulfonamides / therapeutic use
Substances
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Sulfonamides
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Sulfasalazine