Abstract
The experiments on anesthetized cats demonstrated that only a combination of hypoxia and inspiratory resistive loading induced respiratory arrest. The findings suggest that both central and peripheral mechanisms of apnea exist due to functional insufficiency of respiratory muscles as a result of synaptic disorder and excitatory contractility disorder in diaphragmatic muscle fibers.
MeSH terms
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Animals
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Apnea / etiology*
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Apnea / physiopathology
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Carbon Dioxide / physiology
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Cats
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Dyspnea / complications*
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Dyspnea / physiopathology
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Hypoxia / physiopathology
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Muscle Contraction / drug effects
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Muscle Contraction / physiology
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Nitrogen / pharmacology
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Oxygen / pharmacology
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Oxygen / physiology
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Partial Pressure
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Respiration / drug effects
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Respiration / physiology
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Respiratory Muscles / drug effects
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Respiratory Muscles / physiopathology
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Time Factors
Substances
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Carbon Dioxide
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nitrox
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Nitrogen
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Oxygen