Cloning and sequencing of a cDNA encoding the murine vitamin K-dependent protein S

M D Chu; J Sun; P Bird

doi:10.1016/0167-4781(94)90294-1

Cloning and sequencing of a cDNA encoding the murine vitamin K-dependent protein S

Biochim Biophys Acta. 1994 Apr 6;1217(3):325-8. doi: 10.1016/0167-4781(94)90294-1.

Authors

M D Chu¹, J Sun, P Bird

Affiliation

¹ Department of Medicine, Monash Medical School, Box Hill Hospital, Australia.

PMID: 8148380
DOI: 10.1016/0167-4781(94)90294-1

Abstract

A cDNA clone encoding the vitamin K-dependent protein S was isolated from a murine liver cDNA library. Sequencing revealed an open reading frame encoding a 634 amino acid mature protein. Comparison to human and bovine sequences showed a high degree of similarity and the conservation of key residues between the species.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
DNA, Complementary / chemistry
DNA, Complementary / isolation & purification*
Liver / metabolism
Mice
Molecular Sequence Data
Protein S / genetics*
Sequence Alignment

Substances

DNA, Complementary
Protein S

Associated data

GENBANK/Z25469