Abstract
Objective:
To examine thyroid indices in a community referred sample of boys with attention-deficit hyperactivity disorder (ADHD) for evidence of generalized resistance to thyroid hormone (GRTH).
Method:
TSH, T3, and T4 values were gathered prospectively in 53 physician, school, and/or parent referred ADHD subjects, and in 41 age and gender-matched normal controls.
Results:
None were in the range suggestive of global or pituitary thyroid hormone resistance.
Conclusions:
GRTH is rare, and thyroid function should not be measured routinely in nonfamilial ADHD.
Publication types
-
Clinical Trial
-
Comparative Study
-
Randomized Controlled Trial
MeSH terms
-
Attention Deficit Disorder with Hyperactivity / blood
-
Attention Deficit Disorder with Hyperactivity / diagnosis*
-
Attention Deficit Disorder with Hyperactivity / drug therapy
-
Attention Deficit Disorder with Hyperactivity / psychology
-
Child
-
Dextroamphetamine / therapeutic use
-
Double-Blind Method
-
Euthyroid Sick Syndromes / blood
-
Euthyroid Sick Syndromes / diagnosis*
-
Euthyroid Sick Syndromes / genetics
-
Euthyroid Sick Syndromes / psychology
-
Humans
-
Male
-
Methylphenidate / therapeutic use
-
Neurocognitive Disorders / blood
-
Neurocognitive Disorders / diagnosis*
-
Neurocognitive Disorders / drug therapy
-
Neurocognitive Disorders / psychology
-
Thyroid Function Tests*
-
Thyroid Hormones / blood
Substances
-
Thyroid Hormones
-
Methylphenidate
-
Dextroamphetamine