Early-onset respiratory failure caused by severe congenital neuromuscular disease

D L Sandler; D J Burchfield; J A McCarthy; A M Rojiani; W H Drummond

doi:10.1016/s0022-3476(05)83148-8

Early-onset respiratory failure caused by severe congenital neuromuscular disease

J Pediatr. 1994 Apr;124(4):636-8. doi: 10.1016/s0022-3476(05)83148-8.

Authors

D L Sandler¹, D J Burchfield, J A McCarthy, A M Rojiani, W H Drummond

Affiliation

¹ Department of Pediatrics, Univeristy of Florida College of Medicine, Gainesville.

PMID: 8151483
DOI: 10.1016/s0022-3476(05)83148-8

Abstract

Two unrelated infants with low Apgar scores, pneumothoraces, and severe pulmonary hypertension were treated with extracorporeal membrane oxygenation while receiving chemical sedation and neuromuscular paralysis. After decannulation from extracorporeal membrane oxygenation, hypotonia and hypoventilation persisted. Neurologic evaluation confirmed that both infants had a congenital myopathy.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Extracorporeal Membrane Oxygenation
Fatal Outcome
Humans
Infant, Newborn
Male
Neuromuscular Diseases / complications
Neuromuscular Diseases / congenital*
Persistent Fetal Circulation Syndrome / complications*
Persistent Fetal Circulation Syndrome / therapy
Respiratory Insufficiency / etiology*