Inosiplex for localized herpes zoster in childhood cancer patients: preliminary controlled study

Antimicrob Agents Chemother. 1978 Sep;14(3):495-7. doi: 10.1128/AAC.14.3.495.

Abstract

By multiple criteria, inosiplex-a reputed stimulator of virus-sensitized lymphocytes-had no demonstrable therapeutic effects in a preliminary controlled study of patients with localized herpes zoster and cancer. Lymphocytes from the six drug-treated patients were no more responsive to varicella-zoster antigen and phytohemagglutinin than were lymphocytes from seven patients who received a placebo.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Child
  • Clinical Trials as Topic
  • Double-Blind Method
  • Herpes Zoster / complications
  • Herpes Zoster / drug therapy*
  • Humans
  • Immunity, Cellular / drug effects
  • Inosine / analogs & derivatives*
  • Inosine Pranobex / pharmacology
  • Inosine Pranobex / therapeutic use*
  • Neoplasms / complications
  • Placebos

Substances

  • Placebos
  • Inosine
  • Inosine Pranobex