Riboflavin production by Aspergillus terreus from beet-molasses

Microbiologia. 1993 Dec;9(2):118-24.

Abstract

Aspergillus terreus was used for riboflavin (vitamin B2) production in a medium containing beet molasses as the sole carbon source. Growth and the vitamin production of the fungus were markedly affected by the composition of the culture medium. A maximum riboflavin yield was achieved at the late exponential growth phase (16 day-old cultures) in the presence of (g/l): centrifuged beet-molasses, 90; L-asparagine, 1; MgSO4.7H2O, 0.5; K2HPO4/kH2PO4 (1:1), 5; and the medium initially adjusted to pH 8.

MeSH terms

  • Asparagine / metabolism
  • Aspergillus / growth & development
  • Aspergillus / metabolism*
  • Culture Media
  • Fermentation
  • Glucose / analysis
  • Hydrogen-Ion Concentration
  • Industrial Microbiology
  • Kinetics
  • Magnesium Sulfate / pharmacology
  • Molasses*
  • Phosphates / pharmacology
  • Potassium Compounds / pharmacology
  • Riboflavin / biosynthesis*
  • Vegetables

Substances

  • Culture Media
  • Phosphates
  • Potassium Compounds
  • Asparagine
  • Magnesium Sulfate
  • potassium phosphate
  • Glucose
  • Riboflavin