The fragile-X syndrome: a growing gene causing familial intellectual disability

J Intellect Disabil Res. 1994 Feb:38 ( Pt 1):1-8. doi: 10.1111/j.1365-2788.1994.tb00342.x.

Abstract

The fragile-X syndrome is the most common cause of familial intellectual disability. Recently, the gene related to the fragile-X syndrome [the 'fragile-X mental retardation'-1 (FMR-1) gene] has been isolated. In this review, clinical and molecular aspects of the fragile-X syndrome, current benefits and future prospects are discussed.

Publication types

  • Review

MeSH terms

  • Female
  • Fragile X Syndrome / diagnosis
  • Fragile X Syndrome / genetics*
  • Fragile X Syndrome / psychology
  • Genetic Carrier Screening
  • Genetic Testing
  • Humans
  • Intellectual Disability / diagnosis
  • Intellectual Disability / genetics*
  • Intellectual Disability / psychology
  • Intelligence / genetics
  • Male
  • Pedigree
  • Phenotype