Regulation of thymidylate synthase in human colon cancer cells treated with 5-fluorouracil and interferon-gamma

Adv Exp Med Biol. 1993:339:143-51; discussion 165-7. doi: 10.1007/978-1-4615-2488-5_16.

Authors

E Chu¹, C J Allegra

Affiliation

¹ NCI-Navy Medical Oncology Branch, National Cancer Institute, NIH, Bethesda, Maryland 20889.

PMID: 8178713
DOI: 10.1007/978-1-4615-2488-5_16

No abstract available

MeSH terms

Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Cell Survival / drug effects
Colonic Neoplasms / drug therapy*
Colonic Neoplasms / enzymology
Colonic Neoplasms / pathology
Fluorodeoxyuridylate / metabolism
Fluorouracil / therapeutic use
Humans
Interferon-gamma / therapeutic use
Nucleic Acids / metabolism
Thymidylate Synthase / drug effects*
Tumor Cells, Cultured

Substances

Nucleic Acids
Fluorodeoxyuridylate
Interferon-gamma
Thymidylate Synthase
Fluorouracil