Cigarette smoking and functional ovarian cysts

Am J Epidemiol. 1994 Apr 15;139(8):781-6. doi: 10.1093/oxfordjournals.aje.a117074.

Abstract

This population-based case-control study assessed the effect of current cigarette smoking on the risk of functional ovarian cyst development. Cases were all 15-39 year-old enrollees of Group Health Cooperative of Puget Sound (GHC) who had either an inpatient primary diagnosis of functional ovarian cyst in 1988 or 1989 (n = 61) or an outpatient primary diagnosis of functional ovarian cyst at five GHC primary care clinics (n = 37). Controls were randomly selected enrollees matched to cases on age, primary care clinic, and enrollment date (n = 239). A total of 36.7% of cases and 20.5% of controls were determined by medical record review to be current smokers. Compared with women who were not current smokers, the relative risk of a diagnosed functional ovarian cyst among smokers was 2.0 (95% confidence interval 1.1-3.5). This finding, in an area of little previous research, provides a promising lead in the investigation of the etiology of functional ovarian cysts and the effects of smoking on ovarian function in general.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Case-Control Studies
  • Confidence Intervals
  • Female
  • Health Maintenance Organizations
  • Humans
  • Logistic Models
  • Matched-Pair Analysis
  • Ovarian Cysts / diagnosis
  • Ovarian Cysts / epidemiology*
  • Ovarian Cysts / etiology
  • Population Surveillance
  • Risk
  • Risk Factors
  • Smoking / adverse effects*
  • Smoking / epidemiology
  • Washington / epidemiology