Structure-activity relationships of new taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III

J Med Chem. 1994 May 13;37(10):1408-10. doi: 10.1021/jm00036a004.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alkaloids / chemical synthesis
  • Alkaloids / pharmacology*
  • Animals
  • Antineoplastic Agents, Phytogenic / chemical synthesis
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Drug Screening Assays, Antitumor
  • Female
  • Humans
  • Mice
  • Mice, Nude
  • Models, Molecular
  • Structure-Activity Relationship
  • Taxoids*
  • Triterpenes / chemical synthesis
  • Triterpenes / pharmacology*
  • Tumor Cells, Cultured

Substances

  • Alkaloids
  • Antineoplastic Agents, Phytogenic
  • Taxoids
  • Triterpenes
  • baccatin III
  • 10-deacetylbaccatine III