In vivo 2D 1H NMR of mdx mouse muscle and myoblast cells during fusion: evidence for a characteristic signal of long chain fatty acids

B Gillet; B T Doan; C Verre-Serrie; B Barbere; G Berenger; S Morin; J Koenig; M Peres; A Sebille; J C Beloeil

doi:10.1016/0960-8966(93)90091-w

In vivo 2D 1H NMR of mdx mouse muscle and myoblast cells during fusion: evidence for a characteristic signal of long chain fatty acids

Neuromuscul Disord. 1993 Sep-Nov;3(5-6):433-8. doi: 10.1016/0960-8966(93)90091-w.

Authors

B Gillet¹, B T Doan, C Verre-Serrie, B Barbere, G Berenger, S Morin, J Koenig, M Peres, A Sebille, J C Beloeil

Affiliation

¹ Laboratoire de RMN Biologique, ICSN-CNRS, Gif-sur-Yvette, France.

PMID: 8186688
DOI: 10.1016/0960-8966(93)90091-w

Abstract

We have previously demonstrated that 2D 1H NMR is suitable for studying cerebral metabolism. The same technique was used to study the hind leg muscle of normal (C57BL10) and dystrophic (mdx) mice. The results were compared to preliminary results for cultured muscle cells to determine the origin of fatty acid signals.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aging / physiology
Animals
Cell Fusion*
Cells, Cultured
Fatty Acids / analysis*
Hydrogen
Magnetic Resonance Spectroscopy / methods
Mice
Mice, Inbred C57BL
Mice, Neurologic Mutants
Muscles / metabolism
Muscles / physiology*
Muscular Dystrophy, Animal / metabolism*

Substances

Fatty Acids
Hydrogen