[Toxicity of levamisole in adjuvant chemotherapy for colorectal cancer]

Rev Med Interne. 1993;14(9):821-4. doi: 10.1016/s0248-8663(05)81139-7.
[Article in French]

Abstract

We studied the levamisole toxic effects in adjuvant therapy for colorectal cancer. The therapy toxic effects on 127 patients were statistically more important in the levamisole-treated group compared to patients treated with folinic acid and 5-fluorouracil alone. Randomized studies in progress will demonstrate the real therapeutic value of levamisole.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / surgery
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Chemotherapy, Adjuvant
  • Colorectal Neoplasms / drug therapy*
  • Colorectal Neoplasms / surgery
  • Combined Modality Therapy
  • Fluorouracil / administration & dosage
  • Humans
  • Leucovorin / administration & dosage
  • Levamisole / adverse effects*
  • Levamisole / therapeutic use
  • Retrospective Studies

Substances

  • Levamisole
  • Leucovorin
  • Fluorouracil